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It causes low blood flow to your limbs. Skin, muscles and nerves in the affected limb can then become damaged or die because they aren’t receiving the blood they need. The overall management of clti ischemia is reviewed

The clinical manifestations and diagnosis of clti, the approach to revascularization, as well as techniques for surgical and endovascular revascularization are reviewed separately. The plaque eventually forms a complete blockage in several arteries Clti is a clinical syndrome defined by the presence of pad in combination with rest pain, gangrene, or a lower limb ulceration >2 weeks duration.

It is a severe condition that increases the risk for limb loss or major amputation.

Despite advancements in treatments, providing timely and equitable care remains challenging. It can happen when peripheral artery disease becomes severe. Clti happens when plaque buildup from pad gets worse over a period of weeks, months or years

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