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This first systematic review of paratesticular tumors describes clinical and radiographic characteristics stratified by malignant or benign histology Neoplastic benign epididymal cyst (most common epididymal mass) scrotal tunica cysts tunica vaginalis cyst tunica albuginea cyst spermatic cord lipoma scrotal hemangioma Adenomatoid tumor mesothelioma well differentiated papillary mesothelial tumor collecting duct and rete testis tumors

Adenocarcinoma of epididymis melanotic neuroectodermal tumor papillary cystadenoma other tumors Paratesticular lesions have a long list of differential diagnoses Leiomyosarcoma liposarcoma metastases primary follicular lymphoma of testis

A paratesticular mass may derive from a number of structures that surround the testis within the scrotum

Most commonly, they derive from the spermatic cord Pathology the masses can be categorized as benign (70%) or malignant (30%) Tumors of the testicular tunics, including the tunica vaginalis and tunica albuginea, also form a crucial subset of paratesticular appendageal tumors These may include benign lesions like mesothelial cysts or malignant entities such as mesotheliomas.

Paratesticular tumors encompass a variety of histologies that represent a minority of testicular tumors Although the generalizability of findings is limited by publication bias and heterogeneity of reported data from retrospective studies, this is the first comprehensive review on the clinical presentations, radiographic findings, and. Lipoma of the spermatic cord is a popular benign paratesticular tumour and in the epididymis, the most common is adenomatoid tumour followed by leiomyoma, fibroma, haemangioma, neurofibroma and papillary cystadenoma. Ultrasound (us) is the primary modality for evaluation of scrotal pathology, including the characterisation of a paratesticular lesion

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